Biological sampleBlood today, with additional sample types investigated by application.
Measurement and technology
Measure broadly when discovery matters. Focus when the question is known.
miRoncol connects biological samples, microRNA measurement, AI-assisted pattern recognition and application-specific validation in one platform.
The measurement approach depends on the research question, intended use, required breadth, validation stage and delivery pathway.
Connected platformFour layers
Broad or focused measurementNext-generation sequencing (NGS) for a wide profile. Targeted polymerase chain reaction (PCR) for a defined signature.
microRNA intelligenceAI-assisted models recognize disease-associated patterns within the microRNA profile.
Validated applicationA focused use advances only with application-specific evidence.
Complementary measurement strategies
NGS preserves the possibilities. PCR provides the focus.
Next-generation sequencing (NGS) captures a wide profile. Polymerase chain reaction (PCR) measures a selected signature efficiently. The methods serve different stages of discovery, longitudinal research and focused assay development.
Broad measurement
NGSNext-generation sequencing
Preserve a wider field of view.
Next-generation sequencing (NGS) captures a broad measured microRNA panel. When the retained data remains suitable, it may support new analytical questions as research develops.
- Broad profiling and discovery
- Longitudinal research optionality
- Potential reanalysis of retained data
- Greater analytical and cost infrastructure
Focused measurement
PCRPolymerase chain reaction
Measure a defined signature efficiently.
Targeted polymerase chain reaction (PCR) is appropriate when a supported set of microRNAs has been selected for a specific research, monitoring or testing application.
- Selected microRNA signature
- Focused monitoring or testing
- Potentially scalable, lower-cost delivery
- Application-specific assay validation
The shared foundation
A biological sample becomes useful intelligence through three connected steps.
Consistent collection creates comparable data. AI-assisted models interpret microRNA patterns. For clinical delivery, an accredited laboratory must validate, operate and report the test within the requirements of its jurisdiction.
01 · SAMPLE
Collect a consistent biological sample
Blood is the current foundation. Saliva, urine and other sample types require application-specific research.
02 · COMPUTATION
Interpret microRNA patterns with AI
miRoncol uses AI-assisted models to evaluate disease-associated patterns within the microRNA profile alongside quality controls and biological context.
03 · CANADIAN LDT PATHWAY
Why miRoncol partnered with OncoHelix
In Canada, a laboratory-developed test is validated and performed within a clinical laboratory operating under provincial oversight. miRoncol brings the microRNA science and AI model. OncoHelix provides the CPSA-accredited laboratory environment for method validation, quality-controlled testing and physician-directed reporting. Together, the partnership creates the path from published research to a Canadian clinical laboratory service.
Technology disciplineBroad measurement does not justify broad claims.
ComparabilityMethods and batches must remain analytically compatible.
Model validationPerformance must be tested for the defined use.
Clinical contextComputational insight supports, rather than replaces, care.
Next platform question
How does continuing measurement create personal context?
Explore healthy baselines, sustained change, intervention and responsible reanalysis of earlier profiles.