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What Are miRNAs?

Small molecules with big impact on cancer biology

MicroRNAs (miRNAs) are tiny fragments of RNA that regulate how genes are expressed in cells. Though only about 20 nucleotides long, they play a powerful role in controlling cellular activity — including processes linked to cancer development.

Scientific Recognition

  • The first human miRNA was discovered in 2000
  • Since then, hundreds of miRNAs have been identified, each with unique roles in regulating cell behaviour
  • Their importance was confirmed when the 2024 Nobel Prize in Medicine recognized the discovery of microRNAs and their role in gene regulation

How miRoncol Uses miRNAs

The miRoncol Real-time Multi-Cancer Early Risk Assessment measures the expression of hundreds of circulating miRNAs and applies advanced AI to identify patterns linked to cancer biology.

  • Biological sensitivity: miRNAs capture subtle cellular changes
  • Multi-cancer coverage: A single test can assess risk across more than a dozen solid tumour types
  • Meaningful insight: Results provide a real-time snapshot of cancer-associated biological activity

Benefits of a miRNA-Based Approach

  • Detects early molecular changes not visible through imaging or physical exams
  • Captures shared biological signals across many cancers
  • Provides meaningful, actionable insights for health-conscious individuals and physicians
  • Demonstrated high sensitivity in detecting early-stage cancers across multiple tumour types

Next Step

Understanding miRNAs is the first step in appreciating how they can transform cancer prevention.

By tapping into these molecular signals, the miRoncol test offers a new way to see what’s happening in your body today.